1. Introduction to the Research Team

The team will focus on applied basic research and development in the breeding, cultivation and utilization, physiological metabolism, and active components of characteristic edible/medicinal fungi resources in Yunnan Province. Through artificial cultivation of high-value edible/medicinal fungi and domestication of wild edible mushrooms in Yunnan Province, we aim to provide technical support for the establishment and development of the Modern Industrial College of Edible Fungi.

2. Specific Research Directions

• (1) Metabolic regulation and high-value utilization of bioactive components in rare edible/medicinal fungi.

• (2) Domestication, cultivation, and elite strain development of wild edible mushrooms in Yunnan Province.

• (3) Diversity and molecular phylogenetics of macrofungi in Yunnan Province.

3. Research Projects

• (1) National Natural Science Foundation of China, The induction and regulation mechanism of Lauraceae culture mediums on the triterpenoid anabolism of Taiwanofungus camphoratus. Main objectives: elucidating regulatory mechanisms of transcription factors and key synthase genes during triterpenoid synthesis in Taiwanofungus camphoratus induced by Lauraceae culture substrates; deciphering the biosynthetic metabolism of triterpenoid compounds in Taiwanofungus camphoratus through terpenoid substrate interaction with Lauraceae culture media.

• (2) Xingdian Talent Support Program in Yunnan Province, Discovery and evaluation of bioactive components in Taiwanofungus camphoratus. Main objectives: discovery and functional evaluation of bioactive components in Taiwanofungus camphoratus with elucidation of key gene regulatory mechanisms; preparation of high-purity natural bioactive monomeric compounds from Taiwanofungus camphoratus.

4. Team Leader

Yuan Zheng (Professor, zhengyuan_001@126.com)

5. Team Members

De He (Associate professor, 1419615009@qq.com)

Juan Li (Senior Lab Specialist, lijuan@swfu.edu. cn )

Yanmei Li (Lecturer, 850634707@qq.com)

Wenwu Yang (Lecturer, wenwuy25@163.com)

Gengshen Wang (Lecture, wanggengshen@swfu.edu.cn)

6. Selected Publications

• [1] Yadong Zhang, Yi Wang, Xiaolong Yuan, Hongling Zhang, Yuan Zheng. Genomic features of Taiwanofungus gaoligongensis and the transcriptional regulation of secondary metabolite biosynthesis. Journal of Fungi, 2024, 10(12): 826.

• [2] Yadong Zhang, Liangyan Liu, Dong Wang, Xiaolong Yuan, Yuan Zheng, Yi Wang. Isolation and identification of bioactive compounds from Antrodia camphorata against ESKAPE pathogens. Plos One, 2023, 18(10): e0293361.

• [3] Jiaojiao Chen, Zhang Zhang, Yi Wang, Xiaolong Yuan, Juan Wang, Yuming Yang, Yuan Zheng. Transcriptome analysis of Antrodia cinnamomea mycelia from different wood substrates. Mycobiology, 2023, 51(1): 49-59.

• [4] Zhang Zhang, Yi Wang, Xiaolong Yuan, Yana Luo, Maniya Luo, Yuan Zheng. Effects of culture mechanism of Cinnamomum kanehirae and C. camphora on the expression of genes related to terpene biosynthesis in Antrodia cinnamomea. Mycobiology, 2022, 50(2): 121-131.

• [5] Jiang B, Cao Z, Yang D, Wang Y, Ma Y, Zhang S, Zhan H, Yu L, Wang S, Li, J*. Abnormalities in male gametophytes development responsible for low seed set of Peudosasa subsolida. PLoS ONE, 2025 20(1): e0316083.

• [6] Yang, D.; Li, J*.; Wang, S.; Yu, L.; Zhan, H.; Ma, Y. Abnormalities in Stamen and Ovary Development Responsible for Low Seed Set of Dendrocalamus hamiltonii Nees et Arn. ex Munro. Forests 2023, 14, 2282.

• [7] Yingchun Ma, Bowen Li, Dejia Yang, Shuguang Wang, Lixia Yu, Hui Zhan & Juan Li*. An optimal genomic DNA extraction method for shoots of four Dendrocalamus species based on membership function analysis. BioTechniques, 2023, 76 (3): 1-10.

• [8] Li Yanmei, Yue Xiaoguang, Xiang Fei, Mao Dechang, Cao Yong, XiongZhi, Luan Yunpeng*; Effect of Codonopsis foetens on Deferribacteres in constipation predominant intestine tumor: differential analysis. Saudi Journal of Biological Sciences, 2019, 26(3): 395-401.

• [9] He De, Wen JF, Chen WQ, Lu SQ, Xin D-D. Identification, characteristic and phylogenetic analysis of type II DNA topoisomerase gene in Giardia lamblia. Cell Research，2005,15(6): 474-482.

• [10] GengShen Wang, Qing Cai, Yan-Jia Hao, Tolgor Bau, ZuoHong Chen, MeiXiang Li, Navarro David, Nattapol Kraisitudomsook & Zhu-Liang Yang, 2023. Phylogenetic and taxonomic updates of Agaricales, with an emphasis on Tricholomopsis. Mycology 15(2): 180-209.